The IUSTI World + IUSTI Europe 2018 Congress will take place in the academic oasis of Trinity College Dublin. In choosing the theme "The Appliance of Science", we wish to emphasise the great practical advances that science has brought to our day-to-day clinical practice with patients, and to public health. IUSTI 2018 in Dublin will be a great and memorable congress, not only for the programme content, but also for meeting our colleagues and gaining new ideas and concepts.